Professional Medical Societies Strongly Recommend Taking the Lowest Effective Dose for the Shortest Period of Time1
The US Food and Drug Administration and the European Medicines Agency have mandated regulatory language and strongly recommend:
All nonsteroidal anti-inflammatory drugs (NSAIDs) should be administered at the lowest effective dose for the shortest period of time while taking into account patient-specific risk factors and clinical needs.
This guiding principle applies to all NSAIDs.
- Anderson JL, Adams CD, Antman EM, et al. ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 guidelines for the management of patients with unstable angina/non-ST-elevation myocardial infarction) developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine. J Am Coll Cardiol. 2007;50(17):e1-e157.